| Elihu Root | Montreal, Ottawa | Official visit at the invitation of the Governor-General. | January 18–22, 1907 |
| Charles Evans Hughes | Montreal | Addressed meeting of Canadian Bar Association. | September 4–6, 1923 |
| Frank Billings Kellogg | Ft. Erie | Attended dedication of the "Peace Bridge" between Buffalo, New York and Ft.
Erie. | August 7, 1927 |
| Frank Billings Kellogg | Ottawa | Official visit. | February 8–10, 1928 |
| Henry Lewis Stimson | Toronto | Dedicated the Peace Monument during an unofficial visit. | June 12–14, 1930 |
| Cordell Hull | Toronto | Returned visit by Prime Minister Mackenzie King. | October 22–23, 1937 |
| Cordell Hull | Quebec | Attended Quebec Conference with President Roosevelt. | August 20–24, 1943 |
| Dean Gooderham Acheson | Ottawa | Attended 7th Session of the North Atlantic Council. | September 15–20, 1951 |
| Dean Gooderham Acheson | Ottawa | Met with Canadian officials and attended a Cabinet meeting. | November 21–22, 1952 |
| John Foster Dulles | Ottawa | Official visit. | March 17–19, 1955 |
| John Foster Dulles | Ottawa | Attended meeting of the Joint U.S.-Canadian Commission on Trade and Economic
Affairs. | September 25–26, 1955 |
| John Foster Dulles | Kingston, Ottawa | Personal and private visit. Met informally with Prime Minister
Diefenbaker. | July 26–28, 1957 |
| John Foster Dulles | Ottawa | Accompanied President Eisenhower on an informal visit. | July 8–11, 1958 |
| Christian Archibald Herter | Ottawa | Informal meeting with Prime Minister Diefenbaker and Secretary for External Affairs
Green. | July 11, 1959 |
| David Dean Rusk | Ottawa | Met with Prime Minister Diefenbaker and Secretary for External Affairs
Green. | August 24–26, 1962 |
| David Dean Rusk | Ottawa | Attended NATO Ministerial Meeting. | May 20–24, 1963 |
| David Dean Rusk | Ottawa | Attended a meeting of the Joint U.S.-Canadian Committee on Trade and Economic
Affairs. | April 30, 1964 |
| William Pierce Rogers | Montreal | Accompanied President Nixon to the 10th Anniversary ceremonies of the St. Lawrence
Seaway. | June 27, 1969 |
| William Pierce Rogers | Ottawa | Attended a meeting of the Joint U.S.-Canadian Committee on Trade and Economic
Affairs. | November 23–24, 1970 |
| William Pierce Rogers | Ottawa | Accompanied President Nixon on a State visit. | April 13–15, 1972 |
| Henry A. (Heinz Alfred) Kissinger | Ottawa | Attended NATO Ministerial Meeting. | June 17–19, 1974 |
| Henry A. (Heinz Alfred) Kissinger | Montreal | Addressed American Bar Association on international law. | August 11, 1975 |
| Henry A. (Heinz Alfred) Kissinger | Ottawa | Met with Secretary for External Affairs MacEachen. | October 14–15, 1975 |
| Cyrus Roberts Vance | Ottawa | Signed the Great Lakes Water Quality Agreement. | November 21–22, 1978 |
| Cyrus Roberts Vance | Ottawa | Signed a nuclear cooperation agreement. | April 23, 1980 |
| Alexander Meigs Haig | Ottawa | Accompanied President Reagan on a State visit. | March 10–11, 1981 |
| Alexander Meigs Haig | Ottawa, Montebello | Accompanied President Reagan to Economic Summit Meeting. | July 19–21, 1981 |
| George Pratt Shultz | La Sapiniere | Attended NATO Ministerial Meeting. | October 2–3, 1982 |
| George Pratt Shultz | Ottawa | Met with Secretary for External Affairs MacEachen. | October 24–25, 1982 |
| George Pratt Shultz | Halifax (Nova Scotia) | Signed the Great Lakes Phosphorus Load Reduction Agreement. | October 17–20, 1983 |
| George Pratt Shultz | Toronto | Met with Secretary for External Affairs Clark. | October 15–16, 1984 |
| George Pratt Shultz | Quebec | Accompanied President Reagan. | March 17–18, 1985 |
| George Pratt Shultz | Calgary (Alberta) | Met with Secretary for External Affairs Clark. | October 27–28, 1985 |
| George Pratt Shultz | Halifax (Nova Scotia) | Attended NATO Ministerial Meeting. | May 29–30, 1986 |
| George Pratt Shultz | Ottawa | Met with Secretary for External Affairs Clark. | November 21, 1986 |
| George Pratt Shultz | Ottawa | Accompanied President Reagan on an official visit. | April 5–6, 1987 |
| George Pratt Shultz | Windsor (Ontario) | Met with Secretary for External Affairs Clark. | July 2, 1987 |
| George Pratt Shultz | Ottawa | Signed the Arctic Cooperation Agreement. | January 11, 1988 |
| George Pratt Shultz | Toronto | Accompanied President Reagan to the Economic Summit Meeting. | June 19–21, 1988 |
| James Addison Baker | Ottawa | Accompanied President Bush on a working visit. | February 10, 1989 |
| James Addison Baker | Ottawa | Attended Open Skies Ministerial Conference of NATO and Warsaw Pact Foreign
Ministers. | February 11–13, 1990 |
| James Addison Baker | Ottawa | Discussed the Persian Gulf crisis with Prime Minister Mulroney. | January 13–14, 1991 |
| Warren Minor Christopher | Vancouver | Accompanied President Clinton to a summit meeting with Russian President
Yeltsin. | April 2–4, 1993 |
| Warren Minor Christopher | Ottawa | Accompanied President Clinton on a state visit. | February 23–24, 1995 |
| Warren Minor Christopher | Halifax (Nova Scotia) | G-7 Economic Summit. | June 15–17, 1995 |
| Madeleine Korbel Albright | Vancouver | Attended APEC Foreign and Trade Ministerial and Summit Meetings. | November 21–25, 1997 |
| Madeleine Korbel Albright | Ottawa, Hull | Met with Prime Minister Chretien and Foreign Minister Axworthy. | March 9–10, 1998 |
| Colin Luther Powell | Quebec | Accompanied President Bush to the Summit of the Americas. | April 20–22, 2001 |
| Colin Luther Powell | Gander (Newfoundland) | Gave an interview en route to Iceland. | May 13, 2002 |
| Colin Luther Powell | Whistler (British Columbia) | Attended a G-8 Foreign Ministers’ Meeting. | June 12–13, 2002 |
| Colin Luther Powell | Ottawa | Met with Foreign Minister Graham. | November 14, 2002 |
| Colin Luther Powell | Ottawa | Accompanied President Bush. | November 30, 2004 |
| Condoleezza Rice | Ottawa | Met with Prime Minister Martin and Foreign Minister Pettegrew. | October 24–25, 2005 |
| Condoleezza Rice | Halifax, Stellarton (Nova Scotia) | Commemorated 9/11/01 and met with Foreign Secretary MacKay. | September 11–12, 2006 |
| Condoleezza Rice | Ottawa | Attended Security and Prosperity Partnership of North America Meeting. | February 23, 2007 |
| Hillary Rodham Clinton | Niagara Falls (Ontario) | Commemorated the 100th anniversary of the Canada-U.S. Boundary Waters Treaty, and
met with Foreign Minister Cannon. | June 13, 2009 |
| Hillary Rodham Clinton | Montreal | Attended the Haiti Ministerial Preparatory Conference. | January 25, 2010 |
| Hillary Rodham Clinton | Ottawa, Gatineau | Attended a meeting of the Foreign Ministers of the Arctic Coastal States and a
meeting of the G-8 Foreign Ministers. | March 29–30, 2010 |
| Hillary Rodham Clinton | Wakefield (Quebec) | Attended the North American Foreign Ministers’ Meeting. | December 13, 2010 |
| John Forbes Kerry | Ottawa | Met with Prime Minister Stephen Harper and Foreign Minister John Baird. | October 28, 2014 |
| John Forbes Kerry | Iqaluit | Attended the Arctic Council Ministerial meeting. | April 24, 2015 |
| John Forbes Kerry | Quebec | Attended the North American Foreign Ministerial Meeting. | January 29, 2016 |
| John Forbes Kerry | Ottawa | Attended the North American Leaders Summit with President Obama. | June 28–29, 2016 |
| Rex W. Tillerson | Ottawa | Met with President Justin Trudeau and Foreign Minister Chrystia
Freedland. | December 19, 2017 |
| Rex W. Tillerson | Vancouver | Co-hosted the Vancouver Foreign Ministers’ Meeting on Security and Stability on the
Korean Peninsula with Canadian Foreign Minister Chrystia Freeland. | January 15–17, 2018 |
| Michael R. Pompeo | Charlevoix | Accompanied President Trump to the G–7 meetings. | June 9, 2018 |
| Michael R. Pompeo | Ottawa | Met with Prime Minister Justin Trudeau and Foreign Minister Chrystia
Freeland. | August 22, 2019 |
| Antony Blinken | Ottawa, Montreal | Met with Prime Minister Justin Trudeau and Foreign Minister Mélanie Joly. | October 27–28, 2022 |
